Estradiol / Estriol / Pregnenolone Troche

This compounded formulation integrates the potent vasomotor support of estradiol with the gentle, protective profile of estriol and the neuro-modulating benefits of pregnenolone to provide comprehensive endocrine restoration. By utilizing a troche dosage form, the active ingredients are absorbed directly through the buccal mucosa, effectively bypassing first-pass hepatic metabolism and optimizing systemic bioavailability. This clinical approach ensures a more stable therapeutic window while offering a convenient, titration-friendly alternative to traditional oral therapies for patients seeking balanced hormone optimization.