Magnesium Sulfate + Serine + Taurine Injection (Calm Your Farm / CYF SHOT)

Magnesium Sulfate + Serine + Taurine Injection (Calm Your Farm / CYF SHOT)

Available presentation(s): 10, 50 mL. Verify the exact concentration and total active quantity on the prescription and dispensing label.

Introduction: A compounded combination of magnesium sulfate, serine and taurine. Magnesium has recognised clinical uses, but this named combination has no established approved indication or validated regimen for anxiety, relaxation or wellness.

Dosage: No standard combination dose exists. Prescribe the exact volume and corresponding milligrams of each component, route, dilution/rate, frequency and monitoring. Base magnesium exposure on renal function and total magnesium from all sources.

Mechanisms of Action: Replaces magnesium, modulates neuromuscular transmission and calcium movement, stabilises excitable membranes and reduces acetylcholine release at high concentrations. Serine contributes to amino-acid and phospholipid metabolism, while taurine modulates osmoregulation and calcium handling; clinical synergy has not been established.

Contraindications & Precautions: Contraindications include heart block or myocardial damage where clinically relevant and severe renal failure without close monitoring. Monitor reflexes, respiratory rate, urine output, blood pressure and serum magnesium during high-dose therapy. Calcium gluconate should be available for toxicity management.

Interactions: Additive neuromuscular blockade with neuromuscular blockers; additive CNS/respiratory depression with sedatives; hypotension with calcium-channel blockers. Separate incompatible parenteral medicines. Interactions of serine/taurine in the compounded mixture are insufficiently characterised.

Adverse Reactions / Side Effects: Flushing, warmth, nausea, hypotension, lethargy and local irritation are common dose/rate effects. Toxicity causes loss of reflexes, respiratory depression, bradycardia, heart block and cardiac arrest.

Pregnancy & Breastfeeding: Use magnesium in pregnancy only for recognised indications/protocols. The combination lacks pregnancy and lactation safety data and should not be used for routine wellness.

Storage: Store under the conditions stated on the Optimus dispensing label and product-specific worksheet. Protect from light where labelled. Do not freeze unless explicitly validated. Maintain cold chain if the label requires refrigeration. Do not use after the assigned beyond-use date or if there is visible particulate matter, precipitation, colour change, loss of container integrity or evidence of improper storage. Once entered, follow the validated in-use time; do not assume a compounded vial is multi-dose.

References

• New Zealand Formulary (NZF), current online edition; product-specific approved data sheets where available; USP Pharmaceutical Compounding—Sterile Preparations; and Optimus Healthcare validated formulation, sterility/endotoxin controls and assigned beyond-use date.
• DailyMed. Magnesium Sulfate Injection—prescribing information, current edition. https://dailymed.nlm.nih.gov/
• NIH Office of Dietary Supplements. Health Professional Fact Sheets (vitamins and minerals), current online editions. https://ods.od.nih.gov/factsheets/list-VitaminsMinerals/